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Applications of fermentation antifoaming agents in industry?
Release Date:
2020-12-09
When microorganisms are used to produce foods such as alcoholic beverages and soy sauce, as well as pharmaceuticals like antibiotics and vitamins, foaming is a common phenomenon. Particularly during fermentation processes that rely on air for agitation, substantial foam is generated, often filling the fermenter. This foam not only complicates the microbial cultivation process but also poses significant challenges in downstream operations, including cell recovery, concentration, and product separation.
Fermentation antifoaming agent Its applications are extremely broad, particularly in the industrial sector—do you have a specific understanding of this? Let’s explore it together below.
When microorganisms are used to produce foods such as alcoholic beverages and soy sauce, as well as pharmaceuticals like antibiotics and vitamins, foaming is a common phenomenon. Particularly in fermentation processes that rely on air for agitation, substantial foam is generated, often filling the fermenter. This foam not only complicates the microbial cultivation process but also poses significant challenges during subsequent operations, including cell recovery, concentration, and product separation.
Fermentation antifoaming agent The main types are polyether-based and silicone-based. When adding these two kinds of defoamers, customers must subject them to sterilization according to their specific application conditions, with a sterilization temperature of 130°C.
After sterilization, defoamers are typically added using one of two methods:
The first method involves adding a defoaming agent to the base material, along with the microbial strain, carbon source, nitrogen source, and other nutrients, to suppress foam formation during fermentation; in this case, an organosilicone‑based defoamer is preferable.
The second addition method involves fed‑batch feeding during fermentation, with foam levels in the fermenter monitored via a sight glass and fed‑batch additions performed intermittently.
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